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目的：观察腹腔镜胆囊切除术患者全麻插管后气腹对肺通气、肺顺应性和循环的影响。方法：监测３０例患者气腹前、气腹后１０，２０，３０ｍｉｎ的肺顺应性（Ｃｍｐｌ）、气道峰值压力（Ｐｅａｋ）、动脉血二氧化碳分压（ＰａＣＯ２）、呼气末二氧化碳分压（ＰＥＴＣＯ２）、舒张压（ＤＢＰ）、心率（ＨＲ）、心率收缩压乘积（ＲＰＰ）的变化。结果：气腹后各时相的Ｃｍｐｌ比气腹前明显降低（Ｐ＜０．０１），ＰａＣＯ２，ＰＥＴＣＯ２和Ｐｅａｋ增比气腹前升高（Ｐ＜０．０１），气腹后ＤＢＰ升高（Ｐ＜０．０１），ＨＲ加快（Ｐ＜０．０５），ＲＰＰ值增大（Ｐ＜０．０５）。结论：气腹后肺顺应性降低，气道压力增加，肺通气受影响，体内二氧化碳蓄积；血管张力增加，心率增快，心肌氧耗增加，麻醉期间应加强呼吸和循环的监护
Objective: To observe the effects of pneumoperitoneum on pulmonary ventilation, pulmonary compliance and circulation after general anesthesia with laparoscopic cholecystectomy. Methods: The lung compliance (Cmpl), peak airway pressure (PaCO2), end-tidal carbon dioxide partial pressure PETCO2), DBP, heart rate (HR) and heart rate systolic pressure product (RPP). Results: The Cmpl after pneumoperitoneum was significantly lower than that before pneumoperitoneum (P <0.01), PaCO2, PETCO2 and Peak increased significantly (P <0.01) (P <0.01), HR increased (P <0.05) and RPP increased (P <0.05). Conclusions: After pneumoperitoneum, the lung compliance is decreased, the airway pressure is increased, the pulmonary ventilation is affected, the body is captivated by carbon dioxide, the vascular tension is increased, the heart rate is increased and the myocardial oxygen consumption is increased. During the anesthesia, respiratory and circulatory monitoring should be strengthened