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目的:探讨泮托拉唑联合麦滋林治疗胃溃疡长期疗效。方法:将胃溃疡并HP感染的72例患者随机分为治疗组与对照组。标准三联疗法根除HP后,治疗组应用泮托拉唑联合麦滋林;对照组仅用泮托拉唑。结果:疗程结束后复查胃镜观察黏膜组织学改变试验组均显著优于对照组(P<0.05);随访1 a内溃疡复发率治疗组2.9%,对照组24.2%,两组比较有统计学差异(P<0.05)。结论:泮托拉唑联合麦滋林能提高胃溃疡愈合质量,降低复发率。
Objective: To investigate the long-term effect of pantoprazole and mazherin in the treatment of gastric ulcer. Methods: 72 patients with gastric ulcer and HP infection were randomly divided into treatment group and control group. Standard triple therapy to eradicate HP, the treatment group used pantoprazole combined with Mai Zilin; control group only with pantoprazole. Results: After the end of treatment, gastroscopy examination of mucosal histological changes in the experimental group were significantly better than the control group (P <0.05); follow-up 1 a within the ulcer recurrence rate of 2.9% in the treatment group, 24.2% in the control group, the two groups were statistically significant (P <0.05). Conclusion: Pantoprazole combined with mazolin can improve the quality of gastric ulcer healing and reduce the recurrence rate.