麦迪霉素在试管内对钩端螺旋体具有较明显抗菌作用,但其作用较缓慢,没有青霉素那种剧烈的裂解钩体效应,可部分解决临床上出现的加重反应。现将与麦迪霉素同类的红霉素作抗菌试验以比较之。 实验材料 1.抗生素 ①麦迪霉素:四川抗菌素工业研究所制备,每安瓿20万单位。批号:102。 ②红霉素:上海第四制药厂出品注射用乳糖酸红霉素,每瓶25万单位。批号:780125-1。 Midecamycin in the test tube to Leptospira more obvious antibacterial effect, but its role is relatively slow, there is no such kind of severe cleavage hook body penicillin effect can be partially resolved clinically aggravating reaction. Now with erythromycin and midecamycin antibacterial test for comparison. Experimental materials 1. Antibiotics ① midecamycin: Sichuan Institute of antibiotics prepared, each ampoule 200,000 units. Lot: 102. ② erythromycin: Fourth Shanghai Pharmaceutical Factory injection of erythromycin lactobionate, 250,000 units per bottle. Lot number: 780125-1.