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目的对艾滋病病毒感染孕产妇采取服用抗逆转录病毒药物等干预措施,降低艾滋病母婴传播的发生率。方法按照全国预防艾滋病母婴传播的方案,2012年1月~2013年12月对来宾市81例感染艾滋病病毒产妇及其所生82例婴儿(双胞胎1例)按疗程给予足量的抗逆转录病毒药物。按照全国预防艾滋病母婴阻断技术方案要求在婴儿出生42d、12个月和18个月进行随访3次并进行艾滋病早期诊断抗体检测。结果 81例艾滋病病毒阳性孕产妇中74例按疗程服用抗逆转录病毒药物,服药率91.36%。82例艾滋病病毒阳性孕产妇所生婴儿按疗程服用抗逆转录病毒药物,服药率100%。对产后婴儿按照全国预防艾滋病母婴阻断技术方案要求在婴儿出生42d、12个月和18个月进行追踪随访并进行HIV抗体检测,共检出1例艾滋病抗体阳性婴儿,婴儿艾滋病抗体阳性率为1.22%,艾滋病母婴传播阻断效果显著。结论应用抗逆转录病毒药物对感染艾滋病病毒产妇及其所生婴儿进行艾滋病母婴阻断综合干预,对减少艾滋病母婴传播有重要意义。
Objective To reduce the incidence of mother-to-child transmission of HIV in HIV-infected pregnant women by taking anti-retroviral drugs and other interventions. Methods According to the national program of preventing mother-to-child transmission of AIDS, 81 pregnant women with HIV and 82 infants (twins) born in Laibin from January 2012 to December 2013 were given adequate antiretroviral therapy Viral drugs. In accordance with the national program of prevention of mother-to-child transmission of HIV / AIDS, the babies were followed up for 3 times at 42 days, 12 months and 18 months of their birth, and their antibodies for early diagnosis of AIDS were detected. Results Seventy-four HIV-positive pregnant women took antiretroviral drugs according to the course of treatment, with a medication rate of 91.36%. 82 cases of HIV-positive pregnant women gave birth to infants according to the course of taking antiretroviral drugs, medication rate of 100%. Postpartum infants were followed up for 42 days, 12 months and 18 months according to the national program of prevention of mother-to-child transmission of HIV / AIDS prevention and follow-up and HIV antibody testing was conducted. One case of AIDS-positive infants was detected, and the positive rate of AIDS antibody in infants 1.22%, HIV-positive mother-to-child transmission of blocking effect was significant. Conclusion The application of antiretroviral drugs to HIV / AIDS-infected mothers and infants born with HIV / AIDS and maternal and infant interdiction interventions is of great importance in reducing mother-to-infant transmission of HIV / AIDS.