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目的探讨充血性心力衰竭患者血浆同型半胱氨酸浓度与左心室射血分数的相关性。方法选择2013年3月至2015年9月丽江市人民医院收治的200例充血性心力衰竭患者为研究对象,收集患者年龄,性别及体质量指数等,完善超声心动图检查及心肌标志物检查,使用Spearman单因素分析对数据进行相关性分析。结果在充血性心力衰竭患者中,血浆同型半胱氨酸浓度与左心室射血分数呈负相关(r=0.31,P<0.05,y=-11.16x+656.26)。结论在充血性心力衰竭患者中,血浆同型半胱氨酸浓度与左心室射血分数呈负相关,针对血浆同型半胱氨酸的治疗可以有效改善慢性心功能衰竭患者左心室射血分数。
Objective To investigate the correlation between plasma homocysteine concentration and left ventricular ejection fraction in patients with congestive heart failure. Methods From March 2013 to September 2015, 200 cases of patients with congestive heart failure admitted to Lijiang People’s Hospital were enrolled in this study. The age, sex and body mass index of patients were collected. Echocardiography and myocardial markers were examined. Data were analyzed for correlation using Spearman’s one-way analysis. Results Plasma homocysteine concentrations were negatively correlated with left ventricular ejection fraction in patients with congestive heart failure (r = 0.31, P <0.05, y = -11.16x + 656.26). Conclusions In patients with congestive heart failure, plasma homocysteine concentration is negatively correlated with left ventricular ejection fraction. Treatment with plasma homocysteine can effectively improve left ventricular ejection fraction in patients with chronic heart failure.