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４７例急性心肌梗塞（ＡＭＩ）患者按发病年龄随机分成三组，进行尿激酶（ＵＫ）溶栓疗效的对比研究。结果表明，１２小时内溶栓的４７例ＡＭＩ患者再通率、死亡率和并发症发生率分别为５５．３％、１４．９％和８．５％。６小时内溶栓再通率老年组（５０％）明显低于青年组（８０％）和老年前期组（７０％）。老年组住院病死率为２５．９％，且有出血并发症发生，而青年组和老年前期组无一例死亡且无一例出血并发症发生。提示ＵＫ溶栓疗效与患者年龄有关，老年人溶栓疗效较差，病死率和出血并发症发生率较高。
47 patients with acute myocardial infarction (AMI) according to the age of onset were randomly divided into three groups, urokinase (UK) thrombolysis comparative study. The results showed that the rate of recanalization, mortality and complications in 47 patients with AMI thrombolyzed within 12 hours were 55.3%, 14.9% and 8.5%, respectively. Thrombolysis recanalization rate within 6 hours in the elderly group (50%) was significantly lower than that in the youth group (80%) and the pre-senile group (70%). In-patient mortality was 25.9% in the elderly group, with bleeding complications, but none and no bleeding complications in the youth and pre-elderly groups. Prompt UK thrombolytic efficacy and patient age, thrombolysis in the elderly poor efficacy, mortality and higher incidence of bleeding complications.