目的观察植物甾醇酯治疗非酒精性脂肪肝的临床疗效。方法将60例非酒精性脂肪肝患者按受试者脂肪肝等级分级分为试验组和对照组,每组30例,试验组每天食用植物甾醇酯1.35 g,服用时间为60d;对照组采用空白对照。观察干预人群服用植物甾醇酯后非酒精性脂肪肝的改变情况,血中总胆固醇的改变情况。采用χ2检验、t检验和秩和检验等统计方法对所收集和检测的资料进行统计分析。结果用植物甾醇酯60 d后,试验组的总胆固醇水平[(5.32±0.79)mmol/L]较同组试验前[(6.21±0.89)mmol/L]和对照组试验后[(5.83±1.00)mmol/L]有所下降,差异均有统计学意义(P<0.05)。试验组食用植物甾醇酯后脂肪肝程度有所减轻(Z=2.378,P<0.05)。结论植物甾醇酯有降低非酒精性脂肪肝、总胆固醇的功效。 Objective To observe the clinical efficacy of phytosterol ester in the treatment of non-alcoholic fatty liver disease. Methods Sixty patients with non-alcoholic fatty liver were divided into test group and control group according to their grade of fatty liver. Each group had 30 patients. The test group consumed 1.35 g phytosterol ester per day for 60 days, while the control group used blank Control. Observe the changes of non-alcoholic fatty liver in the intervention crowd after taking phytosterol ester, and change of total cholesterol in the blood. The data collected and tested were statistically analyzed by χ2 test, t test, rank sum test and other statistical methods. Results Compared with the control group [(6.21 ± 0.89) mmol / L] and [(5.83 ± 1.00) mmol / L], the total cholesterol level in the test group ) mmol / L] decreased, the differences were statistically significant (P <0.05). Test group edible plant sterol ester fatty liver was reduced (Z = 2.378, P <0.05). Conclusions Phytosterol esters have the effect of reducing non-alcoholic fatty liver and total cholesterol.