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轮状病毒是世界性婴儿腹泻的重要病原,许多影响轮状病毒腹泻自然病程的因素尚需探讨。作者对118例2岁以下急性腹泻婴儿的口服液疗对照试验进行了部分临床研究。并采用多因素统计分析方法(逐步回归分析法,算法语言为WANG-BASIC)对影响患儿止泻时间的35种有关因素和影响腹泻总病程时间的33种有关因素进行了综合分析,国内尚未见此类研究结果发表。分析结果发现喂养是影响止泻时间和总病程时间的最重要因素,与临床观察一致。并对不同喂养与腹泻的关系,轮状病毒性腹泻的饮食、治疗原则等问题提出了初步见解。
Rotavirus is an important pathogen of infant diarrhea in the world. Many factors affecting the natural course of rotavirus diarrhea need to be explored. The authors conducted a partial clinical study of oral control trials of 118 infants under 2 years of age with acute diarrhea. A total of 35 factors affecting the diarrhea time and 33 factors influencing the total duration of diarrhea were analyzed by multivariate statistical analysis (stepwise regression analysis and the algorithm language is WANG-BASIC) See the results of these studies published. The results showed that feeding was the most important factor affecting the time of diarrhea and the duration of the disease, consistent with the clinical observation. And the different feeding and diarrhea, rotavirus diarrhea diet, treatment principles and other issues put forward a preliminary view.