目的　建立胃灵颗粒的制备工艺及质量控制方法 ,通过药理实验研究胃灵颗粒对消化性溃疡的愈合作用。 方法 　采用水煎煮提取方法制备胃灵颗粒 ,用薄层色谱法控制质量 ,用大鼠乙酸型慢性溃疡模型和幽门结扎胃液分析测定法 ,观察该药的抗溃疡作用和对胃溃疡愈合质量的影响。结果 　胃灵颗粒可显著促进胃溃疡的愈合 ,且能明显减少胃溃疡愈合创面再生组织的炎症细胞浸润 ,提高胃溃疡的愈合质量。结论 　胃灵颗粒能有效提高消化性溃疡的愈合质量 Objective To establish the preparation process and quality control methods of Weiling Granules, and to study the healing effect of Weiling Granules on peptic ulcers through pharmacological experiments. Methods Wei Ling granules were prepared by water decoction and extraction method. The quality was controlled by thin-layer chromatography. The rat chronic acetic acid ulcer model and pylorus-ligated gastric fluid were used to analyze the anti-ulcer effect and the healing quality of gastric ulcer. influences. Results Weiling granules can significantly promote the healing of gastric ulcer, and can significantly reduce the inflammatory cell infiltration in the healing tissue of gastric ulcer healing and improve the healing quality of gastric ulcer. Conclusion Weiling granule can effectively improve the healing quality of peptic ulcer