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1988～1990年,Arizona大学做了关于幕上恶性神经胶质瘤的间质高温放疗的Ⅰ期研究。间质热疗首先是间质导管植入。在获得CT扫描的4～5小时内做植入,将复合后装塑料导管(治疗管)和测温导管一并插入肿瘤中心及周围1.5cm的范围内,并借助于环形模板固定于头部。第二步是将可调温性磁铁粒植入后装导管内,磁铁植入后组织的热度取决于磁铁从磁场的能量吸收。植入组织达到的最后温度决定于植入性质、血流水平、磁铁的间隙和磁场强度。热疗时将病人的头放入直径为30cm的磁场诱导系统中,磁场诱导磁铁产生电流,电流又使磁铁产热,通过传导使植入中心及周围组织的
From 1988 to 1990, the University of Arizona conducted a phase I study of hyperthermal hyperthermia in supratentorial malignant gliomas. Interstitial hyperthermia first is interstitial catheter implantation. Implantation was performed within 4 to 5 hours after obtaining the CT scan, and the composite post-installed plastic catheter (therapeutic tube) and the temperature-measuring catheter were inserted into the center of the tumor and the surrounding 1.5 cm range, and fixed to the head by means of the annular template . The second step is to implant the adjustable temperature magnetic particles into the post-installed catheter. The heat of the tissue after the magnet is implanted depends on the energy absorption of the magnet from the magnetic field. The final temperature reached by the implanted tissue depends on the nature of the implants, the level of blood flow, the gap between the magnets and the magnetic field strength. When hyperthermia, the patient’s head into the diameter of 30cm magnetic field induction system, the magnetic field induced magnet current, the current in turn make the magnet heat, through the implantation of the implant center and the surrounding tissue