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目的:探讨直肠癌术后复发的组织间插植放射治疗技术及疗效。方法:1996年2月～1998年10月本院治疗直肠癌Miles术后会阴部局部复发10例,其中伴阴道受侵3例。体外照射40～50Gy后行组织间插植高剂量率192Ir后装治疗,施源管5～25根,剂量3～10Gy/次,总量26～30Gy。结果:CR3例,PR5例,PD2例。2例在治疗后出现局部复发,2例出现会阴部放射性溃疡,均为10Gy/次的患者。3年生存率60%(6/10),其中2例带瘤生存。结论:组织间插植放射治疗是直肠癌术后复发的有效治疗方法,高剂量率放射治疗的分次剂量不宜过高,尤其是会阴皮肤及阴道受侵者。
Objective: To investigate the technique and efficacy of interstitial implantation radiotherapy for postoperative recurrence of rectal cancer. Methods: From February 1996 to October 1998, 10 cases of perineal recurrence were found in Miles after operation in our hospital, including 3 cases with vaginal invasion. In vitro irradiation 40 ~ 50Gy interplanting high dose rate 192Ir after treatment, Shiyuan tube 5 to 25, the dose of 3 ~ 10Gy / time, the total 26 ~ 30Gy. Results: CR3 cases, PR5 cases, PD2 cases. Two patients had local recurrence after treatment, and 2 patients had perineal radioactive ulcer, both with 10 Gy / time. The 3-year survival rate was 60% (6/10), of which 2 patients survived. Conclusion: The interstitial implantation of radiation therapy is an effective treatment for the recurrence of rectal cancer. The dose of high-dose radiation therapy should not be too high, especially for the perineal skin and vagina.