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目的 :探讨支气管哮喘患者长期吸入糖皮质激素的副作用。方法 :检测 30例哮喘患者在吸入糖皮质激素前后的骨密度、血压及血糖 ,30例健康成年人做为对照组。结果 :吸入后半年 ,未见血糖、血压升高者 ;有 2例接近更年期女性患者吸入后骨无机质密度 (BMD)降至正常范围以下 ,但与治疗前及对照组比差异无显著性。结论 :长期吸入糖皮质激素对成年支气管哮喘患者的血糖、血压无影响 ,对骨密度基本无影响 ,但对极个别年龄较大的妇女可能导致骨密度下降
Objective: To investigate the long-term side effects of inhaled corticosteroids in patients with bronchial asthma. Methods: The bone mineral density, blood pressure and blood glucose of 30 asthmatic patients before and after glucocorticoid inhalation were measured, and 30 healthy adults were used as the control group. Results: In the first half of inhalation, no blood sugar and blood pressure were found. In 2 cases, the bone mineral density (BMD) after inhalation was reduced to below the normal range after inhalation, but there was no significant difference between before and after treatment. Conclusion: Long-term inhaled glucocorticoids have no effect on blood glucose and blood pressure in patients with adult bronchial asthma, but have no effect on BMD, but some of the older women may result in decreased BMD