论文部分内容阅读
目的:探讨15-甲基前列腺素(PGF2α,欣母沛)用于治疗宫缩乏力所致产后出血的安全性和有效性。方法:采用随机对照临床研究的方法选择237例产后出血的产妇,在第三产程常规子宫肌壁注射催产素20 U后,随机分入治疗组(使用15-甲基前列腺素子宫肌壁注射)或对照组(继续静脉滴注催产素加强宫缩处理),用容积法和称重法测量比较产后用药前后出血量。结果:不论剖宫产或阴道产,使用15-甲基前列腺素后,欣母沛组在继续出血量方面较催产素组明显减少(P<0.05)。结论:使用15-甲基前列腺素治疗宫缩乏力所致产后出血是安全有效的。当治疗失败时应仔细查找其他导致产后出血的原因。
Objective: To investigate the safety and efficacy of 15-methyl prostaglandin (PGF2α) in the treatment of postpartum hemorrhage caused by uterine atony. Methods: A total of 237 postpartum hemorrhagic mothers were recruited in a randomized controlled clinical study. 20 U of oxytocin was injected into the uterine muscle wall of the third stage of labor and then randomly assigned to the treatment group (using 15-methyl prostaglandin uterine muscle wall injection) Or control group (to continue intravenous oxytocin to strengthen contractions), volumetric method and weighing method to measure the amount of bleeding before and after the postpartum medication. Results: After cetuximab or vaginal birth, the use of 15-methyl prostaglandin, Xin-Pei group continued bleeding in the amount of oxytocin group was significantly reduced (P <0.05). Conclusion: The use of 15-methyl prostaglandin in the treatment of uterine inertia due to postpartum hemorrhage is safe and effective. When the treatment fails should carefully find the other causes of postpartum hemorrhage.