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目的对药品不良反应(adverse drug reaction,ADR)进行分析,为临床合理用药提供依据。方法 2010年1月—2012年12月收集上报的ADR 86例进行回顾性分析。结果合并用药19例,占22.09%;单独用药67例,占77.91%。86例ADR共涉及34种药品,其中抗菌药最多12种,发生ADR占56.98%。皮肤及其附件损害最多,占38.37%。86例ADR经对症处理全部治愈。结论 ADR具有普遍性,应避免不必要的多种药物联用,坚持合理用药,加强医疗机构临床用药管理。
Objective To analyze the adverse drug reaction (ADR) and provide the basis for clinical rational drug use. Methods A total of 86 ADR cases collected from January 2010 to December 2012 were retrospectively analyzed. Results 19 cases of combined medication, accounting for 22.09%; 67 cases of drug alone, accounting for 77.91%. 86 cases of ADR involving 34 kinds of drugs, including up to 12 kinds of antibacterials, the occurrence of ADR accounted for 56.98%. The most damage to the skin and its accessories, accounting for 38.37%. 86 cases of ADR were all cured by symptomatic treatment. Conclusion ADR is universal, should avoid unnecessary combination of multiple drugs, adhere to rational use of drugs, and strengthen the clinical management of medical institutions.