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目的:研究联合醒脑静与纳洛酮治疗急性重度酒精中毒的临床疗效。方法:选取本院2012年12月至2013年12月收治的20例急性酒精中毒患者,随机分为观察组(n=10)和对照组(n=10),两组皆给予基础治疗,对照组在此基础上给予单纯纳洛酮治疗,观察组在此基础上给予醒脑静联合纳洛酮进行联合治疗。结果:对照组和观察组在酒后清醒时间、症状消失时间,痊愈率、总有效率、等方面皆存在显著的统计学差异(P<0.05)。且观察组临床疗效显著优于对照组。结论:醒脑静与纳洛酮联合治疗急性重度酒精中毒,能够显著缩短患者的恢复时间,发挥较好的协同作用,提高患者的临床治疗效果,是一种值得在临床上推广和应用的治疗方法。
Objective: To study the clinical efficacy of combined Xingnaojing and naloxone in the treatment of acute severe alcoholism. METHODS: Twenty patients with acute alcoholism admitted from December 2012 to December 2013 in our hospital were randomly divided into observation group (n = 10) and control group (n = 10). Both groups were given basic treatment. The control group On the basis of this group, only simple naloxone treatment was given, and the observation group was given Xingnaojing combined with naloxone on the basis of the above treatment. Results: There were significant differences between the control group and the observation group in wakefulness after drinking, symptom disappear time, cure rate, total effective rate and so on (P <0.05). The clinical efficacy of the observation group was significantly better than that of the control group. Conclusion: The combination of xingnaojing and naloxone in the treatment of acute severe alcoholism can significantly shorten the recovery time of patients, play a better synergistic effect and improve the clinical effect of the patients, which is worthy of clinical application and treatment method.