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目的:观察盐酸米诺环素软膏治疗慢性牙周炎的临床疗效。方法:选择慢性牙周炎52例(312颗患牙共1872个位点),按照左右牙列自身对照的方法分别设立观察组和对照组,在牙周基础治疗及根面平整后,观察组牙周袋内置入盐酸米诺环素软膏,对照组牙周袋内置入碘甘油。分别记录两组在基线、3个月、6个月时牙龈指数(GI)、牙周袋探诊深度(PD)、附着丧失(AL)的变化情况,并进行比较。结果:牙周治疗后3个月、6个月,两组间GI比较,差异不显著(P>0.05),PD、AL比较,差异显著(P<0.05)。结论:采用盐酸米诺环素软膏治疗慢性牙周炎疗效较好。
Objective: To observe the clinical effect of minocycline hydrochloride ointment in the treatment of chronic periodontitis. Methods: 52 cases of chronic periodontitis (31272 teeth) were selected. The observation group and the control group were established according to the methods of left and right dentition self-control respectively. After periodontal basic treatment and root surface flattening, the observation group Periodontal pockets were built into minocycline hydrochloride ointment, and the control periodontal pockets were filled with iodine glycerin. The changes of gingival index (GI), probing depth (PD) and attachment loss (AL) of the two groups at baseline, 3 months and 6 months were recorded and compared. Results: After 3 and 6 months of periodontal treatment, there was no significant difference in GI between the two groups (P> 0.05). There was significant difference between PD and AL (P <0.05). Conclusion: Minocycline hydrochloride ointment is effective in treating chronic periodontitis.