目的探讨糖化血红蛋白(HbA1c)对妊娠期糖尿病(GDM)的筛查价值及GDM患者的早期护理干预。方法选取2013年6月—2014年2月我院妇产科门诊收治的GDM患者45例(GDM组)、糖耐量异常患者45例(糖耐量异常组)、血糖正常孕妇45例(血糖正常组)。检测3组受试者HbA1c及空腹血糖(FBG),然后行口服葡萄糖耐量试验(OGTT),并对GDM患者进行早期护理干预。结果 GDM患者HbA1c阳性率(88.9%)>OGTT(77.8%)>FBG(42.2%)(P<0.05)。GDM组患者HbA1c、FBG高于其他两组(P<0.05)。结论 HbA1c对GDM患者诊断准确率较高,操作便捷、所需血量少、不易受其他因素的影响,可作为筛查GDM的重要指标。早期护理干预可以辅助临床治疗,帮助GDM患者有效控制血糖。 Objective To investigate the screening value of glycosylated hemoglobin (HbA1c) in gestational diabetes mellitus (GDM) and early nursing intervention in GDM patients. Methods Forty-five patients with GDM (GDM group), 45 patients with impaired glucose tolerance (IGT group), 45 patients with normal blood glucose level (normal blood glucose group) were selected from June 2013 to February 2014 in our hospital. ). HbA1c and fasting blood glucose (FBG) were measured in three groups of subjects, followed by oral glucose tolerance test (OGTT) and early nursing intervention in GDM patients. Results The positive rate of HbA1c in GDM patients (88.9%) was higher than that of OGTT (77.8%) and FBG (42.2%) (P <0.05). HbA1c and FBG in GDM group were higher than those in other two groups (P <0.05). Conclusion The diagnostic accuracy of HbA1c in patients with GDM is high, and it is easy to operate. It needs less blood and is not easily influenced by other factors. It can be used as an important index for screening GDM. Early nursing interventions can assist with clinical treatment to help GDM patients effectively control blood sugar.