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本文应用浅盘凝集试验和精子宫颈粘液接触试验分别检测34对不明原因不育夫妇血清和生殖道局部分泌物中抗精子抗体的发生率。15/34对一方血清抗精子抗体阳性(44.12％),女方阳性率为23.53％,男方阳性率为20.59％。12/27对一方局部抗精子抗体阳性(44.44％),宫颈粘液抗体阳性率为25.92％,精液抗体阳性率为18.52％。5例仅有血清抗体,6例仅有局部抗体,6例兼有血清和局部抗体。结果显示不明原因不育症患者中血清和局部抗精子抗体发生率明显高于生育组,而且血清和局部抗体活性可能不一致。因此在研究免疫不育症时同时检测夫妇双方血清和局部抗精子抗体有重要意义。
In this paper, the use of shallow plate agglutination test and sperm cervical mucus contact test were detected in 34 pairs of unexplained infertility in serum and genital tract secretions of anti-sperm antibodies in the incidence. Seroprevalence of anti-sperm antibody was positive in one of the 15/34 (44.12%) women, 23.53% in the female and 20.59% in the male. 12/27 was positive for local anti-sperm antibody (44.44%), positive rate of cervical mucus antibody was 25.92%, semen antibody positive rate was 18.52%. Only 5 cases of serum antibodies, 6 cases only local antibodies, 6 cases of both serum and local antibodies. The results showed that patients with unexplained infertility serum and local anti-sperm antibody was significantly higher than the reproductive group, and serum and local antibody activity may be inconsistent. Therefore, in the study of immune infertility at the same time testing both the serum and local anti-sperm antibodies have important significance.