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目的:观察中西医结合治疗2型糖尿病胰岛素抵抗的临床疗效,并探讨其作用机制。方法:将80例2型糖尿病患者随机分为两组。对照组40例口服降糖药二甲双胍0.5g,每日3次。治疗组40例在对照组治疗基础上加服养阴清热活血消脂汤,每日1剂,每日服2次。两组均6周为1个疗程,1个疗程后统计疗效。结果:治疗组总有效率78%,对照组总有效率58%,两组比较差异有显著性(P<0.05)。治疗组在降低血糖、空腹胰岛素、改善胰岛素释放率、胰岛素敏感指数方面明显优于对照组,比较差异有显著性(P<0.05或P<0.01)。结论:中西医结合治疗2型糖尿病胰岛素抵抗者能有效减轻症状,改善胰岛素抵抗,对2型糖尿病胰岛素抵抗者有较好的疗效。
Objective: To observe the clinical efficacy of integrated traditional Chinese and western medicine in the treatment of type 2 diabetes insulin resistance and to explore its mechanism. Methods: Eighty patients with type 2 diabetes were randomly divided into two groups. Control group, 40 cases of oral hypoglycemic agents metformin 0.5g, 3 times a day. The treatment group 40 cases in the control group based on the treatment plus Yang Yin Qinghuoxiaozhi soup, 1 day, 2 times a day. Two groups were 6 weeks for a course of treatment, a course of treatment after the statistical effect. Results: The total effective rate was 78% in the treatment group and 58% in the control group. There was significant difference between the two groups (P <0.05). The treatment group was significantly better than the control group in lowering blood glucose, fasting insulin, improving insulin release rate and insulin sensitivity index (P <0.05 or P <0.01). Conclusion: Integrative treatment of type 2 diabetes with insulin resistance can effectively reduce symptoms and improve insulin resistance, type 2 diabetes insulin resistance has a good effect.