由于雌激素对人体具有广泛的生理和药理活性,故其制剂(包括人工合成的甾体和非甾体化合物)成为临床常用的药物,某些合成雌激素(如炔雌醇)也是避孕药的主要成分。雌激素与其他生物活性物质或药物一样,在体内也发生结构转化,最终降解灭活,排出体外。有证据表明,雌激素的某些中间代谢物(如儿茶酚雌激素)本身也有生物活性,很可能是雌激素作用的中介体(Mediators)。研究和阐明雌激素的代谢与生理、药理和毒性的关 Because estrogen has a wide range of physiological and pharmacological activities on the body, its preparations (including synthetic steroids and non-steroidal compounds) have become clinically used drugs. Some synthetic estrogens (such as ethinylestradiol) are also contraceptive Main ingredient Estrogen, like other biologically active substances or drugs, undergoes structural transformation in vivo, eventually deactivating it and excreting it. There is evidence that some of the intermediate metabolites of estrogen, such as catechin estrogen, are also themselves bioactive and are likely to be mediators of estrogen action. Research and elucidate the estrogen metabolism and physiology, pharmacology and toxicity