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目的探讨超声及宫颈粘液评分(CMS)在未破裂卵泡黄素化综合征(LUFS)诊断中的价值。方法应用阴道超声及CMS对26例不孕妇女31个月经周期进行连续监测。结果有7个周期发生LUFS,发生率为22.58%,5例LUFS患者有2例重复发生,再发生率40%,围排卵期CMS持续7天达15分,且下降缓慢;黄体中期血清泌乳素(PRL)水平明显高于正常排卵周期妇女(P<0.05),孕酮降低,但无统计学差异(P>0.05)。结论黄体中期PRL的隐匿性增高可能与LUFS的发生密切相关,定期B超监测结合CMS是诊断LUFS实用和可靠的方法。
Objective To investigate the value of ultrasound and cervical mucus score (CMS) in the diagnosis of luteinized unruptured follicle syndrome (LUFS). Methods Twenty-six infertile women with 31 menstrual cycles were monitored continuously by vaginal ultrasound and CMS. Results The incidence of LUFS in 7 cycles was 22.58%. In 5 LUFS patients, 2 cases were repeated and the recurrence rate was 40%. The CMS in ovulation period lasted for 15 days and decreased slowly. The mid-luteal serum Prolactin (PRL) levels were significantly higher than those in normal ovulation cycles (P <0.05), while progesterone levels were lower but not statistically different (P> 0.05). Conclusion The luteal PRL occlusion may be closely related with the occurrence of LUFS. Periodic B-ultrasound combined with CMS is a practical and reliable method for the diagnosis of LUFS.