论文部分内容阅读
目的探讨极低出生体重儿早发血小板减少症的相关因素。方法选择2011—2013年我院NICU收治的极低出生体重儿进行回顾性研究。根据生后72 h内有无血小板减少症分为早发血小板减少症组和无早发血小板减少症组,对两组患儿临床情况进行比较。结果108例研究对象入选,发生早发血小板减少症45例(41.7%),患儿血小板计数在中位数8天恢复正常。男婴(OR=6.036)、早发感染(OR=8.358)及孕母患妊娠期高血压疾病(OR=5.990)与极低出生体重儿早发血小板减少症相关(P<0.05),胎龄、出生体重、胎膜早破、窒息、产前应用地塞米松、呼吸窘迫综合征等对极低出生体重儿早发血小板减少症无明显影响。结论早发血小板减少症是极低出生体重儿的常见合并症,男婴、早发感染及孕母患妊娠期高血压疾病是极低出生体重儿早发血小板减少症的危险因素。
Objective To investigate the related factors of premature thrombocytopenia in very low birth weight infants. Methods A retrospective study was conducted on very low birth weight children admitted to NICU from 2011 to 2013 in our hospital. According to 72 hours after birth, no thrombocytopenia is divided into premature thrombocytopenia group and no premature thrombocytopenia group, the clinical situation of the two groups were compared. Results A total of 108 subjects were enrolled and 45 cases (41.7%) had premature thrombocytopenia. The platelet count returned to normal after 8 days in children. Premature birth (OR = 8.358) and gestational hypertension (OR = 5.990) were associated with premature thrombocytopenia in very low birth weight infants (P <0.05), gestational age , Birth weight, premature rupture of membranes, asphyxia, prenatal application of dexamethasone, respiratory distress syndrome, etc. have no significant effect on premature thrombocytopenia in very low birth weight infants. Conclusions Premature thrombocytopenia is a common complication of very low birth weight infants. The risk factors for premature thrombocytopenia in very low birth weight infants are low birth weight in male infants, early onset infections and gestational hypertension in pregnant women.