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帕金森病(Parkinson Disease,PD)是由于黑质内多巴胺(DA)能神经元减少超过80%时,纹状体中的神经递质DA和乙酰胆碱之间的相互拮抗作用失调而导致的神经系统疾病。黑质DA神经元的大量减少普遍认为与多种因素参与有关,近年来,诸多研究显示小胶质细胞参与的炎症反应与PD关系密切,其
Parkinson’s disease (Parkinson’s disease, PD) is the nervous system caused by the imbalance of antagonism between the neurotransmitter DA and acetylcholine in the striatum when the dopaminergic neurons in the substantia nigra are reduced by more than 80% disease. Massive reduction of substantia nigra DA neurons is generally considered to be involved in a variety of factors. In recent years, many studies have shown that the microglial inflammatory response is closely related to PD.