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临床试验已经证明,强化他汀类药物治疗对冠心病患者是有益的。大剂量的他汀类药物有良好的临床疗效,但常使患者血浆低密度脂蛋白胆固醇(LDL-C)的浓度降得很低。因此强化降脂治疗的临床有效性和安全性引起关注。Wiviott等学者将每天口服40mg罗苏伐他汀的患者按照以往研究中达到
Clinical trials have shown that intensive statin therapy is beneficial in patients with coronary heart disease. High doses of statins have good clinical efficacy, but often make patients with low concentrations of plasma low-density lipoprotein cholesterol (LDL-C) decreased very low. Therefore, to enhance the clinical efficacy and safety of lipid-lowering treatment caused concern. Wiviott and other scholars will daily oral administration of 40mg rosuvastatin patients as achieved in previous studies