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别嘌醇为次黄嘌呤的异构体,是黄嘌呤氧化酶(XO)的抑制剂,是目前唯一能抑制尿酸合成的药物。临床主要用于:①原发性和继发性高尿酸血症,尤其是尿酸生成过多而引起的高尿酸血症;②反复发作或慢性痛风者;③痛风石;④尿酸性肾结石和(或)尿酸性肾病;⑤有肾功能不全的高尿酸血症。剂型为片剂。2012年1月1日至12月31日,国家药品不良反应监测中心病例报告数据库共收到别嘌醇片不良反应/事件
Allopurinol is an isomer of hypoxanthine, an inhibitor of xanthine oxidase (XO), and is currently the only drug that inhibits uric acid synthesis. Clinical mainly for: ① primary and secondary hyperuricemia, especially hyperuricemia caused by excessive uric acid production; ② recurrent or chronic gout; ③ tophi; ④ uric acid kidney stones and (Or) uric acid nephropathy; ⑤ hyperuricemia with renal insufficiency. The dosage form is a tablet. January 1, 2012 to December 31, 2012, the national ADR surveillance center case report database received allopurine tablets adverse reactions / events