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氧氟沙星和左氧氟沙星注射剂均为目前临床常用的第三代喹诺酮类药物,为了解和比较两药的ADR发生情况及其影响因素,并从临床和经济学相结合的角度对两药临床应用的合理性以及两药所致的ADR进行经济学分析,北京市8家医疗单位(北京积水潭医院、北京宣武医院、北京同仁医院、北京大学第一医院、北京大学第三医院、北京大学人民医院、北京朝阳医院和北京石景山医院)为此进行了为期1年的专项研究。1 资料与方法1.1 病例来源 本调研病历来自2000年10月~2001年9月,上述8家医院中使用氧氟沙星和左氧氟沙星注射剂的全部住院患者。剔除与ADR无关的死亡病例、提前出院的病例。
Ofloxacin and levofloxacin injection are currently the third generation of commonly used quinolone clinical drugs, in order to understand and compare the two ADR incidence and its influencing factors, and from a combination of clinical and economic perspective of the clinical application of both drugs And the economic analysis of the ADR caused by the two drugs. Eight medical institutions in Beijing (Beijing Jishuitan Hospital, Beijing Xuanwu Hospital, Beijing Tongren Hospital, Peking University First Hospital, Peking University Third Hospital, Peking University People’s Hospital , Beijing Chaoyang Hospital and Beijing Shijingshan Hospital) conducted a one-year special study. 1 Materials and Methods 1.1 The source of the case The medical records from October 2000 to September 2001, the above eight hospitals in ofloxacin and levofloxacin injection of all hospitalized patients. Excluding ADR unrelated deaths, early discharge of cases.