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本文报告1973年10～11月在美国L州海湾收获被污染的蚝生吃之后,发生2起甲型肝炎的暴发流行:在H市患病的有263人,在C市有15人。流行病学调查证实,这些人发病前是健康的,在吃生蚝之后2～8周出现了肝炎症状。两地有45人用对流免疫电泳或放射免疫法检测乙型肝炎抗原(HBAg)均为阴性。在H市于1973年10月15日至11月7日,有200例甲型肝炎报告,而在前一年同期仅有32例。上述263例患者中,经调查有243例于2～8周(平均28天)前曾在一家餐馆吃生蚝,另外20例在其他9家饭店吃过生蚝。他们的HBAg均阴性。这个城市所供应的蚝,均从L州海湾运来。
This article reports two outbreaks of hepatitis A that occurred after harvesting polluted oyster raw fish from Gulf Coast, L state, from October to November 1973: 263 sick in H City and 15 in C City. Epidemiological investigation confirmed that these people before the onset of a healthy, 2 to 8 weeks after eating oysters hepatitis symptoms. Forty-five people were negative by both convective or radioimmunoassay for hepatitis B antigen (HBAg). There were 200 cases of hepatitis A reported in H City from October 15 to November 7, 1973, compared with only 32 cases in the same period of the previous year. Of the 263 patients surveyed, 243 had oysters in one restaurant two to eight weeks (an average of 28 days) and another 20 oysters in nine other restaurants. Their HBAg is negative. Oysters supplied in this city are shipped from the Gulf of L state.