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目的探讨山莨菪碱与酚妥拉明治疗婴幼儿重症肺炎的疗效及不良反应。方法回顾性分析86例婴幼儿重症肺炎,86例患儿均采用积极的综合治疗的基础下,根据用药的情况分为山莨菪碱组和酚妥拉明组,山莨菪碱组36例,酚妥拉明组50例。比较两组的疗效、住院天数及不良反应的发生率。结果山莨菪碱组患儿的疗效优于酚妥拉明组(P<0.05),山莨菪碱组患儿的不良反应发生率少于酚妥拉明组(P<0.05),两组的住院天数比较无明显差异(P>0.05)。结论山莨菪碱组治疗婴幼儿重症肺炎效果较酚妥拉明疗效显著且不良反应发生率低。
Objective To investigate the efficacy and adverse reactions of anisodamine and phentolamine in the treatment of infantile severe pneumonia. Methods A retrospective analysis of 86 cases of infants with severe pneumonia, 86 cases of children were treated with positive comprehensive basis, according to the use of drugs were divided into anisodamine group and phentolamine group, anisodamine group of 36 patients, phenol Toramin group of 50 cases. The curative effect, hospitalization days and the incidence of adverse reactions were compared between the two groups. Results The efficacy of anisodamine group was better than that of phentolamine group (P <0.05). The incidence of adverse reactions in anisodamine group was less than that of phentolamine group (P <0.05) No significant difference in the number of days (P> 0.05). Conclusion Anisodamine treatment of severe pneumonia in infants and children than phentolamine significant effect and the incidence of adverse reactions is low.