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目的探讨阿奇霉素联合头孢呋辛酯胶囊治疗上呼吸道感染患儿的临床效果。方法回顾性分析2011年2月至2013年3月泰州市姜堰区王石卫生院收治的上呼吸道感染患儿100例,按就诊顺序将其分为观察组和对照组,各50例。对照组患儿给予阿奇霉素,观察组患儿在对照组基础上口服头孢呋辛酯胶囊,比较两组患儿临床治疗效果、不良反应发生情况及咳嗽、高热消退时间。结果观察组患儿的总有效明显高于对照组,差异有统计学意义(P<0.05);观察组患儿咳嗽、高热消退时间均明显短于对照组,差异均有统计学意义(均P<0.05)。结论小儿上呼吸道感染临床治疗过程中联合使用阿奇霉素、头孢呋辛酯胶囊,安全性高,可明显改善患儿的临床症状及生活现状。
Objective To investigate the clinical effect of azithromycin combined with cefuroxime axetil in children with upper respiratory tract infection. Methods A retrospective analysis of 100 cases of children with upper respiratory tract infection admitted to Wangshi Hospital of Jiangyan District, Taizhou from February 2011 to March 2013 was divided into observation group and control group, 50 cases in each group. The children in the control group were treated with azithromycin. The patients in the observation group were given oral cefuroxime axetil on the basis of the control group. The clinical effects, adverse reactions and the time of cough and fever subside were compared between the two groups. Results The total effective rate in the observation group was significantly higher than that in the control group (P <0.05). The cough and the fever subsided time in the observation group were significantly shorter than those in the control group (all P <0.05). Conclusion The combination of azithromycin and cefuroxime axetil in the clinical treatment of pediatric upper respiratory tract infection has high safety and can obviously improve the clinical symptoms and living status of children.