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目的:探讨难治性癌性腹腔积液有效的治疗方法。方法:恶性腹腔积液患者腹腔穿刺后,予地塞米松预防发热,并注入铜绿假单胞菌制剂,每周1次,连续2～3次。结果:21例患者腹腔注入33次,每例1～3次,平均1.6次,有效率80.9%。3例腹部出现隐痛不适,1例出现肠痉挛,4例腹腔注入地塞米松后仍出现中低度发热。结论:应用铜绿假单胞菌制剂治疗癌性腹腔积液,具有一定效果,副反应较轻微,建议临床进一步推广应用。
Objective: To explore the effective treatment of refractory malignant ascites. Methods: After peritoneal puncture in patients with malignant ascites, dexamethasone was given to prevent fever and injected with Pseudomonas aeruginosa once a week for 2 ~ 3 times. Results: 21 patients were injected intraperitoneally 33 times, 1 to 3 times per case, with an average of 1.6 times, with an effective rate of 80.9%. 3 cases of pain and discomfort in the abdomen, 1 case of intestinal spasm, 4 cases of intra-abdominal injection of dexamethasone still mild to moderate fever. Conclusion: The application of Pseudomonas aeruginosa in the treatment of malignant ascites has certain effect and mild side effects, and it is recommended to further promote the clinical application.