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实验选5～6个月的家兔30只,随机分为实验组(喂胱氨酸和胆固醇)和对照组(喂胆固醇),饲养113天杀死,取主动脉和心脏切片,用组织学和组化方法染色。结果表明实验组和对照组血胆固醇都升高,实验组血硫升高,直接破坏动脉壁,且胆固醇和甘油三脂易沉积于主动脉内膜中,同时冠状动脉肌支发生粥样硬化病变,实验组多于对照组,二者差异非常显著,说明胱氨酸有促进主动脉和冠状动脉肌支粥样硬化早期病变的作用。
In the experiment, 30 rabbits aged 5-6 months were randomly divided into an experimental group (cystine and cholesterol) and a control group (cholesterol fed). The rats were killed for 113 days. Aortic and cardiac sections were taken and histology was used. And staining methods. The results showed that both the experimental group and the control group had elevated blood cholesterol, and the experimental group had elevated blood sulfur, which directly damaged the arterial wall. Cholesterol and triglyceride were easily deposited in the aortic intima, and atherosclerotic lesions developed in the coronary muscle branch. The experimental group was more than the control group. The difference between the two groups was very significant, indicating that cystine can promote the early lesions of atherosclerosis in the aorta and coronary artery branches.