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目的 探讨交感神经皮肤反应 (SSR)检测在评价 2型糖尿病 (T2DM )自主神经损害中的价值。方法 对 10 0例T2DM患者进行SSR检测 ,30例健康志愿者作为对照。结果 2组SSR的起始潜伏期、N波潜伏期、波幅、面积比较差异有显著性意义 (P <0 .0 5 ) ,P波潜伏期差异无显著性意义 (P >0 .0 5 )。T2DM组72例 (72 % )患者至少有一肢SSR异常。血糖控制满意组和血糖控制不良组比较 ,起始和N波潜伏期差异有统计学意义 (P <0 .0 5 ) ,波幅和面积无显著性意义 (P >0 .0 5 )。T2DM组病程 <5年与病程≥ 5年比较 ,潜伏期、波幅、面积差异均无统计学意义 (P >0 .0 5 )。结论 SSR可作为评价T2DM自主神经损害的客观电生理指标 ;T2DM患者SSR与血糖控制水平相关 ,与病程无关。目的 探讨交感神经皮肤反应 (SSR)检测在评价 2型糖尿病 (T2DM )自主神经损害中的价值。方法 对 10 0例T2DM患者进行SSR检测 ,30例健康志愿者作为对照。结果 2组SSR的起始潜伏期、N波潜伏期、波幅、面积比较差异有显著性意义 (P <0 .0 5 ) ,P波潜伏期差异无显著性意义 (P >0 .0 5 )。T2DM组72例 (72 % )患者至少有一肢SSR异常。血糖控制满意组和血糖控制不良组比较 ,起始和N波潜伏期差异有统计学意义 (P <0 .0 5 ) ,波幅和面积无显著性意义 (P >0 .
Objective To investigate the value of sympathetic skin reaction (SSR) in the evaluation of autonomic nerve damage in type 2 diabetes mellitus (T2DM). Methods 100 cases of T2DM patients were detected by SSR, 30 healthy volunteers as a control. Results The onset latency, N wave latency, amplitude and area of SSR in the two groups were significantly different (P <0.05). There was no significant difference in the latency of P wave (P> 0.05). 72 patients (72%) in T2DM group had at least one SSR abnormality. There were significant differences in the latency of onset and N wave between the satisfaction of glycemic control group and the control group of poor glycemic control (P <0.05), while the amplitude and area had no significant difference (P> 0.05). There was no significant difference in latency, amplitude and area between T2DM group (<5 years) and duration (> 5 years) (P> 0.05). Conclusion SSR can be used as an objective electrophysiological index to evaluate the autonomic nerve damage of T2DM. SSR of T2DM patients is related to the level of blood sugar control, but has no relationship with the course of disease. Objective To investigate the value of sympathetic skin reaction (SSR) in the evaluation of autonomic nerve damage in type 2 diabetes mellitus (T2DM). Methods 100 cases of T2DM patients were detected by SSR, 30 healthy volunteers as a control. Results The onset latency, N wave latency, amplitude and area of SSR in the two groups were significantly different (P <0.05). There was no significant difference in the latency of P wave (P> 0.05). 72 patients (72%) in T2DM group had at least one SSR abnormality. There were significant differences in latency of onset and N wave between the control group and those with poor glycemic control (P <0.05), but the amplitude and area had no significant difference (P> 0.05).