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目的为了解该地区出生缺陷发生情况,及时发现影响出生的可疑因素,制定有效地预防措施,以减少出生缺陷儿的出生,提高出生人口素质。方法对2007年-2009年在越秀区监测医院内出生的58 513例围产儿中,男性胎儿30 094例,女性胎儿28 391例,性别不明28例,出生缺陷儿2207例,采用χ2检验进行统计分析。结果出生缺陷的发生与孕母年龄、出生性别有关,孕母年龄在35岁以上其出生缺陷发生率明显升高(P<0.01),男性胎儿出生缺陷发生率高于女性(χ2=14.75,P<0.01)。结论出生缺陷的防治,重在预防,采取有效的预防措施,加强婚前保健,开展优生咨询、普及优生知识,加强孕期保健指导,继续开展、探索产前诊断技术,提高诊断水平,积极进行宫内治疗,加强高危妊娠管理,进行高危孕妇筛查。
Objective To find out the occurrence of birth defects in the area and find out the suspicious factors that affect the birth in time, and to formulate effective preventive measures to reduce the birth of children with birth defects and improve the quality of the birth population. Methods A total of 58 094 cases of male fetuses, 28 391 cases of female fetuses, 28 cases of unknown sex and 2207 cases of birth defects were included in 58 513 cases of perinatally born in Yuexiu District Monitoring Hospital from 2007 to 2009. Statistics were analyzed by χ2 test analysis. Results The incidence of birth defects was related to the age of maternal age and sex at birth. The incidence of birth defects was significantly higher in pregnant women aged 35 years and older (P <0.01), and the incidence of birth defects in males was higher than that in females (χ2 = 14.75, P <0.01). Conclusion The prevention and treatment of birth defects focus on prevention, take effective preventive measures, strengthen premarital health care, carry out prenatal counseling, popularize prenatal knowledge, strengthen the guidance of health care during pregnancy, continue to carry out, explore prenatal diagnosis techniques, improve the diagnostic level, Treatment, strengthen the management of high-risk pregnancy, high-risk screening for pregnant women.