目的 了解和掌握三明市梅毒流行动态,为有关部门防治性病提供决策依据。方法 对1989～1999年全市梅毒疫情资料进行整理分析。结果1989～1999年全市登记性病20 236例,其中梅毒2 322例,占同期性病数的11.47％。1989年首先报告3例,占性病总数的0.37％,1999年报告433例,占17.64％,呈逐年上升趋势。1992年以前每年报告在20例以下,1993年后呈跳跃式上升,1995年起每年报告在300例以上,并出现胎传梅毒、小儿梅毒和晚期隐性梅毒。男女性别比为1.30:1,年龄4天～67岁,职业以工人、个体及无业人员居多,占62.19％,已婚占77.09％,非婚性接触传染占70.20％。 结论 11年来三明市梅毒流行呈逐年上升趋势,早期梅毒占多数,传染性强,如不采取有效措施,今后几年梅毒仍有可能在较高水平流行。 Objective To understand and grasp the epidemic situation of syphilis in Sanming City and provide the basis for decision-making for prevention and treatment of venereal diseases by relevant departments. Methods The data of syphilis epidemic in the whole city from 1989 to 1999 were analyzed. Results A total of 20 236 STDs were registered in the city from 1989 to 1999, including 2322 syphilis cases, accounting for 11.47% of the STDs over the same period. In 1989, 3 cases were firstly reported, accounting for 0.37% of the total number of STDs. 433 cases were reported in 1999, accounting for 17.64%, showing an upward trend year by year. Before 1992, the annual report was below 20 cases and showed a leaping jump after 1993, with more than 300 cases reported annually from 1995 onwards. There were also fetal syphilis, pediatric syphilis and late latent syphilis. The male-to-female sex ratio was 1.30: 1, ranging in age from 4 days to 67 years. Occupations were mostly workers, individuals and unemployed persons, accounting for 62.19%, married 77.09% and non-marital contagion 70.20%. Conclusions Syphilis epidemics in Sanming City have been increasing year by year in the past 11 years. Early syphilis is predominant and contagious. If effective measures are not taken, it is still possible that syphilis will prevail at a relatively high level in the next few years.