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目的探讨胚胎停育患者在生活和工作中的环境行为危险因素。方法采用病例-对照研究对192例胚胎停育患者和192例正常妊娠者进行问卷调查,内容包括研究对象一般情况、生活和工作中的可疑环境行为危险因素等。结果经多因素非条件logistic回归分析,结果显示,年龄大(OR=1.064,95%CI:1.005~1.126)、孕前3个月或孕期吸入二手烟(OR=2.185,95%CI:1.028~4.644)、使用染发剂(OR=2.780,95%CI:1.328~5.821)、居室装修(OR=3.258,95%CI:1.813~5.856)是胚胎停育的危险因素,教育程度高(OR=0.668,95%CI:0.523~0.852)、孕前健康状况良好(OR=0.184,95%CI:0.078~0.435)、主动获取优生知识(OR=0.494,95%CI:0.265~0.920)、孕期情绪状况愉快(OR=0.496,95%CI:0.291~0.845)、孕期与家庭成员关系和睦(OR=0.475,95%CI:0.241~0.934)是胚胎停育的保护因素。结论年龄大、孕前3个月或孕期吸入二手烟、使用染发剂、居室装修可能与胚胎停育的发生有关系,而教育程度高、孕前健康状况良好、主动获取优生知识、孕期情绪状况愉快、孕期与家庭成员关系和睦则可以减少胚胎停育发生。
Objective To investigate the risk factors of environmental behavior in the life and work of patients with embryo stop. Methods A case-control study was conducted in 192 diseased embryos and 192 normal pregnancies. The questionnaires included the general conditions of the study subjects, suspicious environmental and behavioral risk factors in life and work. The results of multivariate non-conditional logistic regression analysis showed that older (OR = 1.064, 95% CI: 1.005-1.126), second-hand smoking during the first trimester or during pregnancy (OR = 2.185, 95% CI: 1.028-4.464 ) With hair dye (OR = 2.780, 95% CI: 1.328-5.821), room decoration (OR = 3.258,95% CI: 1.813-5.856) (OR = 0.494, 95% CI: 0.265-0.920), and had a good mood during pregnancy (OR = 0.94, 95% CI: 0.523-0.852) OR = 0.496, 95% CI: 0.291-0.845). Relationship between family members and pregnancy (OR = 0.475,95% CI: 0.241-0.934) was the protective factor of embryo stop. Conclusion Age, pre-pregnancy or during pregnancy intake of second-hand smoke, the use of hair dye, bedroom decoration may be related to the occurrence of embryo suspension, but a high level of education, good health status before pregnancy, take the initiative to obtain eugenics knowledge, emotional happy during pregnancy, The relationship between pregnancy and family members can reduce the occurrence of embryo suspension.