从云南土壤真菌 0 7 11发酵液乙酸乙酯层浸膏中得到 5个活性成分 ,经光谱数据分析和理化鉴别 ,分别鉴定为邻羟基苯甲酸 (Ⅰ )、4 ,6 二羟基 5 甲基 1(3H)异苯骈呋喃酮 (Ⅱ )、2 甲酰基 3,5 二羟基 4 甲基苯甲酸 (Ⅲ )、N (4 羟基 2 甲氧苯基 )乙酰胺 (Ⅳ )以及麦角甾 7,2 2 二烯 3,6 二酮(Ⅴ ) ,它们对稻瘟霉分生孢子及菌丝体都有一定抑制作用。其中化合物Ⅳ为首次分离得到的天然产物 ,其谱学数据也是首次报道 Five active ingredients were obtained from the ethyl acetate extract of 0 7 11 fermentation broth of Yunnan, and identified as ortho-hydroxybenzoic acid (Ⅰ), 4,6-dihydroxy 5-methyl 1 (3H) isofuranone (Ⅱ), 2 formyl 3,5 dihydroxy 4 methylbenzoic acid (Ⅲ), N (4 hydroxy 2 methoxyphenyl) acetamide (Ⅳ) and ergosterol 7,2 2 diene 3,6 dione (Ⅴ), they have a certain inhibition of Pyricularia grisea conidia and mycelium. Among them, compound Ⅳ was the first natural product isolated, and its spectral data was also reported for the first time