按照国际小鼠标准化术语委员会的规定,近交系是指兄妹交配20代或20代以上,并且继续进行兄妹交配的品系(Staats,1976)。由于生物医学发展的需要,已登记的各类小鼠品系的总数已超过500种。由于种种原因,例如突变和由于管理不善造成的不同品系间的杂交等,小鼠近交系的遗传特性不是永久不变的。这些保留着原有品系名 According to the International Committee for the Standardization of Mouse Terminology, inbred lines refer to siblings who breed for 20 generations or more and continue to breed siblings (Staats, 1976). Due to the needs of biomedical development, the total number of registered various mouse strains has exceeded 500. The genetic character of mouse inbred lines is not permanent due to various reasons such as mutation and crossbreeding between different lines due to mismanagement. These retain the original name of the system