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本文作者为了确定链球菌分泌的神经氨酸酶(NM)在急性链球菌感染后肾炎(APSGN)发病中的作用,对81例APSGN患儿和78例健康儿童血清NM活性及NM水解产物—血清游离唾液酸(FSA)进行了检测。结果:无论血清FSA抑或NM均为APSGN组显著高于正常组,并发现患儿血清FSA与NM变化基本一致,符合率达78.12%.提示NM在AFSGN急性期是增高的;血清NM活性升高是引起FSA升高的主要原
In order to determine the role of streptococcal neuraminidase (NM) in the pathogenesis of acute streptococcal nephritis (APSGN), the authors investigated the effects of streptococcal neutrophil (NM) activity and NM hydrolyzate-serum on 81 children with APSGN and 78 healthy children Free sialic acid (FSA) was tested. Results: Serum FSA or NM were significantly higher in the APSGN group than in the normal group, and found that the changes of serum FSA and NM in children were basically the same, the coincidence rate reached 78.12%, suggesting that NM was increased in AFSGN acute phase and elevated in serum NM Is the main cause of increased FSA