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目的探究甲基强的松龙鞘内注射治疗急性期多发性硬化的临床效果。方法 62例多发性硬化急性期患者,根据住院治疗时间先后及个人情况分为治疗组和对照组,各31例。治疗组采用甲基强的松龙鞘内注射进行治疗,对照组采用甲基强的松龙静脉滴注进行治疗,评价两组患者的治疗效果。结果治疗组治疗总有效率为87.1%,对照组治疗总有效率为67.7%,比较差异具有统计学意义(P<0.05)。结论对急性期多发性硬化患者采用甲基强的松龙静脉滴注治疗,能有效促进患者神经系统的恢复,值得临床推广应用。
Objective To investigate the clinical effect of intrathecal injection of methylprednisolone in the treatment of acute multiple sclerosis. Methods Sixty-two patients with multiple sclerosis at acute stage were divided into treatment group (n = 31) and control group (n = 31) according to the duration of hospitalization and personal circumstances. The treatment group was treated with methylprednisolone intrathecal injection, and the control group was treated with methylprednisolone intravenous infusion to evaluate the therapeutic effect of the two groups of patients. Results The total effective rate of the treatment group was 87.1%, while the total effective rate of the control group was 67.7%. The difference was statistically significant (P <0.05). Conclusion The treatment of acute multiple sclerosis patients with methylprednisolone intravenous infusion can effectively promote the recovery of patients with nervous system, worthy of clinical application.