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目的研究普贝生用于胎膜早破患者引产的临床效果。方法收集我院2009年4月-10月宫颈成熟度较差的胎膜早破产妇80例,排除头盆不称等异常因素,半数作为研究组,经后穹窿给予普贝生促宫颈成熟,对照组给予催产素,比较其临床效果和副作用。结果研究组产程明显缩短,阴道出血量少,胎儿窘迫、新生儿窒息、剖宫产比率明显降低,而产褥感染率无明显增高。结论宫颈成熟度较差,无头盆不称的胎膜早破患者经阴道给予普贝生引产,其促进宫颈成熟效果明显优于催产素,产褥感染率无增高,临床使用安全可靠。
Objective To study the clinical effect of pubezheng on induction of labor in patients with premature rupture of membranes. Methods 80 cases of premature rupture of membranes from April 2009 to October 2009 in our hospital were collected. Excluding the abnormalities such as cephalopelvic disproportion, half of them were taken as the research group. After the fornix, The control group was given oxytocin, comparing its clinical effects and side effects. Results The study group was significantly shorter birth, less vaginal bleeding, fetal distress, neonatal asphyxia, cesarean section rate was significantly reduced, but no significant increase in puerperal infection. Conclusions Cervical maturity is poor. The patients without premature rupture of membranes without vaginal infusions were given vaginal induction of probiotics. The cervical ripening effect was better than that of oxytocin, and the rate of puerperal infection was not increased. The clinical use was safe and reliable.