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几种抗菌药物对壳顶幼虫的毒性试验结果表明：（１）以９６ｈ平均日生长率作为药物对幼虫毒性的观察指标，求出日生长率仅为对照组一半时的药物浓度（９６ＴＬＭ）及安全浓度（ＳＤ）如下：氯霉素６９×１０－６、６．９×１０－６；呋喃西林７２×１０－６、７．２×１０－６；百炎净７７×１０－６、７．７×１０－６；红霉素９７×１０－６、９．７×１０－６；硫酸链霉素４８×１０－６、４．８×１０－６；青霉素钠大于１００×１０－６、１０×１０－６。（２）１３×１０－６的呋喃西林、１３×１０－６的红霉素、１３×１０－６的青霉素钠对幼虫生长均有促进作用。（３）各试验组随药物浓度递增，幼虫活动逐渐被抑制；摄食率及眼点率逐渐下降。高浓度红霉素对摄食的抑制作用最强。
The results of toxicity test of several antibacterials on the top shell larvae showed that: (1) The average daily growth rate of 96h was used as an indicator of toxicity to larvae, and the drug concentration (96TLM), which was only half of the control group, The safe concentration (SD) is as follows: chloramphenicol 69 × 10-6,6.9 × 10-6; nitrofurazone 72 × 10-6,7.2 × 10-6; 100 Yan net 77 × 10-6,7. 7 × 10-6 erythromycin 97 × 10-6, 9.7 × 10-6 streptomycin sulfate 48 × 10-6,4.8 × 10-6; penicillin sodium greater than 100 × 10-6, 10 × 10-6. (2) Nitrofurazone at 13 × 10-6, erythromycin at 13 × 10-6, and penicillin at 13 × 10-6 promoted the growth of larvae. (3) With the increasing of drug concentration in each experimental group, the activity of larvae was gradually inhibited; the feeding rate and eyelination rate decreased gradually. High concentrations of erythromycin on the feeding of the strongest inhibitory effect.