我们已经知道,染色体是基因的载体,它的物质基础是脱氧核糖核酸(DNA),它是决定人体遗传和变异的内因。因此染色体的数量及染色体上基因之间的特定排列顺序和空间关系的完整性对人体的正常发育是必不可少的。如果由于某种内部或外部的原因破坏了染色体的这种完整性,到一定程度,就会引起有关的缺陷和疾病,甚至导致死胎。染色体畸变是突变 We already know that chromosomes are the carrier of genes. Its material basis is DNA, which is the internal factor that determines the genetic and variation of human beings. Therefore, the number of chromosomes and the specific order of the genes in the chromosome and the integrity of the spatial relationship are essential for the normal development of the human body. If for some internal or external reasons destroyed the integrity of chromosomes to a certain extent, it will cause the related defects and diseases, and even lead to stillbirth. Chromosomal aberrations are mutations