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目的：研究感染性休克病人血流动力学改变与其预后的关系。方法：１９例感染性休克患者在抢救中接受肺动脉漂浮导管的临床监测，将其结果与病人的转归进行对照分析。结果：全组患者在给予容量复苏后血流动力学变化呈明显高动力状态。其主要参数变化为心脏指数增加和体循环阻力下降。这两项变化在生存组和死亡组是一致的。但在抢救后的第３天，生存组心脏指数逐渐降至正常，降低的体循环阻力指数逐渐回升；而死亡组则无任何变化。结论：心脏指数的增加与体循环阻力下降有关。因此，改善组织灌注和逆转血管瘫痪状态是决定抢救成败的关键措施。
Objective: To study the relationship between hemodynamic changes and prognosis in septic shock patients. METHODS: Nineteen patients with septic shock were monitored for pulmonary artery floating catheterization during rescue and the results were compared with those of patients. Results: The hemodynamic changes of the whole group of patients after the given volume resuscitation showed obvious high dynamic state. The main parameters changed as the heart index increased and systemic resistance decreased. These two changes are consistent in the survival group and the death group. However, on the third day after rescue, the index of cardiac function in survival group gradually decreased to normal, and the index of resistance to systemic circulation decreased gradually; however, the death group did not change. Conclusion: The increase of cardiac index is related to the decrease of systemic resistance. Therefore, to improve tissue perfusion and reverse the status of vascular paralysis is the key to determining the success or failure of rescue measures.