肿瘤转移至口腔,尤其是口腔软组织极为少见。本文报道1例。 患者为63岁男性,曾患晚期食管癌并行姑息性食管切除术。来口腔门诊要求鉴定牙龈上逐渐增大的肿物。口腔检查见:下颌磨牙区舌侧牙龈上一突出的2cm×1.8cm大小的肉芽性出血肿物,有蒂,未发现其它部位损害及淋巴结肿大,未有溶骨性损害,未见远距离癌肿组织转移。切除后的食管癌诊断为基底细胞样鳞状细胞癌。切除的牙龈肿物主要为包含小基底细胞的未分化癌肿和鳞状成分。非常类似食管癌的组织学特征,进一步的免疫组织化学染色(抗生物素蛋白—生物素复合染色技术)确诊为食管基底细胞样鳞状细胞 The transfer of tumors to the oral cavity, especially oral soft tissue, is extremely rare. This article reported 1 case. The patient, a 63-year-old man, had advanced palliative esophagectomy for advanced esophageal cancer. To come to an oral clinic requires the identification of a gradually enlarged mass on the gum. For oral examination, see a prominent 2cm×1.8cm granuloma with a peduncular mass on the lingual gums of the mandibular molar area. No other lesions and enlarged lymph nodes were found. No osteolytic lesions were found. Cancer metastasis. Resection of esophageal cancer was diagnosed as basal cell-like squamous cell carcinoma. The excised gingival masses are mainly undifferentiated cancers and squamous components containing small basal cells. Very similar to the histological characteristics of esophageal cancer, further immunohistochemical staining (avidin-biotin complex staining technique) confirmed as esophageal basal cell-like squamous cell