目的:探讨解脲支原体及沙眼衣原体与异位妊娠的关系。方法:利用PCR技术对98例输卵管异位妊娠患者(病例组)及90例因子宫病变而切除输卵管的患者(对照组)宫颈分泌物、输卵管组织进行解脲支原体及沙眼衣原体的DNA检测。结果:病例组宫颈分泌物检出解脲支原体DNA34例,阳性率为34.7%,对照组14例,阳性率15.6%;病例组输卵管组织检出解脲支原体DNA28例,阳性率为15.0%,对照组8例,阳性率为8.9%,两组比较差异有显著性(P<0.05)。病例组宫颈分泌物检出沙眼衣原体DNA25例,阳性率为25.5%,对照组9例,阳性率为10.0%;病例组输卵管组织检出沙眼衣原体DNA23例,阳性率为23.5%,对照组5例,阳性率为5.6%,两组比较差异有显著性(P<0.05)。结论:解脲支原体、沙眼衣原体与输卵管妊娠的发生有关。 Objective: To explore the relationship between Ureaplasma urealyticum and Chlamydia trachomatis and ectopic pregnancy. Methods: The DNA of Ureaplasma urealyticum and Chlamydia trachomatis was detected in 98 cases of tubal ectopic pregnancy (case group) and 90 cases of oviduct patients (control group) cervical secretions and fallopian tube tissues by PCR. Results: In the cases of cervical secretions, 34 cases of Ureaplasma urealyticum DNA were detected, the positive rate was 34.7%, while the control group was 14 cases, the positive rate was 15.6%. In the case group, tubal ureaplasma urealyticum DNA was detected in 28 cases, the positive rate was 15.0% Group, 8 cases, the positive rate was 8.9%, the difference between the two groups was significant (P <0.05). Cases of cervical secretions detection of Chlamydia trachomatis DNA in 25 cases, the positive rate was 25.5%, 9 cases in the control group, the positive rate was 10.0%; tuberculosis cases Chlamydia trachomatis DNA 23 cases, the positive rate was 23.5% in the control group of 5 cases , The positive rate was 5.6%, the difference between the two groups was significant (P <0.05). Conclusion: Ureaplasma urealyticum, Chlamydia trachomatis and tubal pregnancy related.