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Th17是新近发现的辅助性T淋巴细胞亚群,其特征是分泌白细胞介素17(IL-17)。目前已发现Th17与诸多自身免疫性疾病密切相关。自身免疫性损伤是病毒性心肌炎发病机制中的重要因素之一,并且与扩张型心肌病的发病有关。因此,研究Th17细胞亚群在心肌炎中的作用十分必要,为进一步揭示心肌炎的发病机制,阻断心肌炎向扩张型心肌病进展提供新的思路。
Th17 is a newly discovered subset of helper T lymphocytes characterized by the secretion of interleukin-17 (IL-17). It has been found that Th17 is closely related to many autoimmune diseases. Autoimmune damage is one of the important factors in the pathogenesis of viral myocarditis, and is related to the pathogenesis of dilated cardiomyopathy. Therefore, the study of Th17 cell subsets in the role of myocarditis is very necessary, in order to further reveal the pathogenesis of myocarditis, block myocarditis to the development of dilated cardiomyopathy provide new ideas.