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本文以１００例血库献血员为正常对照，６０例病毒性肝炎患者为研究对象，在检测了肝炎患者血浆血管性血友病因子相关抗原（ｖＷＦ：Ａｇ）、补体Ｃ＿３含量及白细胞吞噬率变化的同时，对循环血中内皮细胞（ＣＥＣ）的分离和检测方法进行了初步探讨，结果表明，肝炎组ＣＥＣ（３．３３±０．９８／μｌ）较对照组（１．６２±０．８７／μｌ）有显著升高，ｖＷＦ：Ａｇ肝炎组（２２２．１４±５７．３２％）较对照组（９９．３１±１６．５４％）有显著升高（Ｐ＜０．０１）．补体Ｃ３含量肝炎组（６．２３±１．９５ｇ／Ｌ）较对照组（８．２５±１．２９ｇ／Ｌ）降低（Ｐ＜０．０５）。白细胞吞噬率肝炎组（０．３６０±０．０４５）较对照组（０．４３０±０．０７９）有下降趋势（Ｐ＜０．０５）．通过对ＣＥＣ分离检测方法的探讨，有助于直接反映肝病时血管内皮细胞的损伤。
In this study, blood donors from 100 blood banks were used as normal controls and 60 patients with viral hepatitis were enrolled in this study. The levels of vWF: Ag, C_3, leukocyte phagocytosis At the same time, the method of separation and detection of circulating endothelial cells (CEC) was studied. The results showed that CEC in hepatitis group (3.33 ± 0.98 / μl) was significantly higher than that in control group (1.62 ± 0.87 / μl) was significantly higher in vWF: Ag group (222.14 ± 57.32%) than in control group (99.31 ± 16.54%) (P <0.01). The level of complement C3 in hepatitis group (6.23 ± 1.95g / L) was lower than that in control group (8.25 ± 1.29g / L) (P <0.05). The leukocyte phagocytosis rate in hepatitis group (0.360 ± 0.045) was lower than that in control group (0.430 ± 0.079) (P <0.05). Through the discussion of CEC separation and detection methods, it can directly reflect the damage of vascular endothelial cells in liver diseases.