营养指导对慢性阻塞性肺疾病急性加重期治疗前后前白蛋白的影响

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目的探讨营养指导对慢性阻塞性肺疾病急性加重期(AECOPD)患者治疗前后前白蛋白的影响,阐述营养指导在AECOPD治疗中的作用。方法通过对于2012年2月—2013年2月我院呼吸科住院的100例AECOPD患者,随机分为对照组和干预组,干预组给予常规治疗的同时,按照个体化原则给予患者营养指导,包括营养知识教育、膳食指导、改善膳食质量等方法,对照组仅给予常规治疗。采用免疫比浊法检测治疗前后患者前白蛋白的变化并进行对比。结果二组治疗前前白蛋白比较,差异无统计学意义(P>0.05),治疗后与对照组比较,干预组前白蛋白明显高于对照组,差异有统计学意义(P<0.05)。结论营养指导有助于AECOPD患者前白蛋白合成增多,增加患者免疫功能,促进疾病恢复。 Objective To investigate the effect of nutritional guidance on prealbumin in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) before and after treatment, and to elucidate the role of nutritional guidance in the treatment of AECOPD. Methods 100 AECOPD patients hospitalized for respiratory department in our hospital from February 2012 to February 2013 were randomly divided into control group and intervention group. Patients in intervention group were treated with routine therapy and patients were given nutritional guidance according to the principle of individualization, including Nutritional knowledge education, dietary guidance, improving dietary quality and other methods, the control group was given only conventional treatment. Immunoturbidimetric assay before and after treatment in patients with albumin before and after comparison. Results There was no significant difference in albumin before treatment between the two groups (P> 0.05). Compared with the control group, prealbumin in the intervention group was significantly higher than that in the control group after treatment (P <0.05). Conclusion Nutritional guidance can help increase the prealbumin synthesis in patients with AECOPD, increase the patient’s immune function and promote the recovery of the disease.
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