本刊曾刊登《解热镇痛药的再评价》一文(注:见2002年第6期第417页),讨论安乃近在一些国家引起粒细胞缺乏的报告,引发了关于安乃近作为一种镇痛药的优缺点的种种争论。安乃近的化学结构与苯基吡唑酮类的氨基比林相似。上世纪30年代,氨基比林被发现能引起粒细胞缺乏。此后不久发 The publication of the article “Reevaluation of Antipyretic and Analgesic Drugs” (Note: See page 417, p. 417), which discussed the report of the metamorphosis causing agranulocytosis in some countries, led to a report on the use of adnimde as A controversy over the advantages and disadvantages of analgesics. The chemical structure of Analgin is similar to that of phenylpyrazolones. In the 1930s, aminopyrine was found to cause agranulocytosis. Shortly afterwards