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本文通过体外细胞培养的方法，研究了１０例分泌性中耳炎（ＯＭＥ）患儿腺样体的免疫状态，测定体外腺样体淋巴细胞自发性ＤＮＡ合成（ＳＤＳ）及在植物血凝素（ＰＨＡ）刺激下可溶性白细胞介素－２受体（ＳＩＬ－２Ｒ）释放，并以阻塞性睡眠性呼吸暂停综合征患儿作对照。结果，ＯＭＥ患儿腺样体淋巴细胞ＳＤＳ（１７３３５±７０１２ｃｐｍ）较对照组（９３８２±４５５４ｃｐｍ）明显增高（Ｐ＜０．０５），ｓＩＬ－２Ｒ的释放（８６４±２４１ｕ／ｍｌ）也较对照组（４３８±１４５ｕ／ｍｌ）增高（Ｐ＜０．０５），说明ＯＭＥ患儿腺样体淋巴细胞活性较高，可能导致局部免疫异常而引起ＯＭＥ。
In this study, the immune status of adenoid in 10 cases of secretory otitis media (OME) was studied in vitro by cell culture method. The spontaneous DNA synthesis (SDS) of adenoid lymphocytes and the activity of phytohemagglutinin (PHA) Stimulation of soluble interleukin-2 receptor (SIL-2R) release, and obstructive sleep apnea syndrome in children as a control. As a result, the numbers of adenoid lymphocytes in OME children (17335 ± 7012cpm) were significantly higher than those in the control group (9382 ± 4554cpm) (P <0.05), and the release of sIL-2R (864 ± 241u / ml) (438 ± 145u / ml) increased (P <0.05), indicating that the high activity of adenoid lymphocytes in OME children may lead to local immune abnormalities caused by OME.